This book aims to introduce the reader to the broad range of manufacturing techniques currently employed in the growing area of laboratory-on-a-chip technology. Starting from an overview of the current state-of-the-art in lab-on-a-chip devices and their applications, it describes the device design processes. The emphasis is on recent advances in computer-aided design and simulation processes to reduce the cost and time spent in device development. Future trends in lab-ob-a-chip manufacturing technology are discussed. The book contains a broad range of practical examples and the overall perspective will be one of a practical guide. While this book has an overall focus on lab-on-a-chip technologies, the information contained in the book is of general interest to all areas of microfabrication.