The handbook covers the science and applications of biomaterials. It addresses in detail the chemistry, physics and biology that underpin the design of biomaterials and the clinical disciplines in which they are used. Among the topics are: polymer synthesis and characterization, drug and gene vector design, the biology of the host response, immunology and toxicology and-self assembly at the nanoscale. Clinical applications include regenerative medicine, diagnostic systems that rely on innovative contrast and sensing agents, cancer diagnosis and therapy, implantable devices, drug delivery systems, gene vectors, bionanotechnology and tissue engineering.