The second edition of this extremely successful and well-proven book reflects recent developments in the use of hydrolases for organic synthesis. The renowned authors have added a new chapter on protein sources and optimization of biocatalyst performance for organic synthesis, an expanded chapter about directed evolution and a new chapter covering catalytic promiscuity. Furthermore, the sections dealing with dynamic kinetic resolution and immobilization have been substantially updated. Also, new classes of hydrolases, such as haloalkane dehalogenases and organophosphorus hydrolases are now covered.
Thus, the 2nd edition covers an even broader field and provides an excellent overview of stereoselective reactions using hydrolases, such that researchers can solve their own synthetic problems. In all, the book contains over one thousand chemical structures and around 1,800 valuable references.