The objective is to propose, in a single volume, a comparative and functional approach of the spine (vertebral system) in Tetrapods, from amphibians to primates, including humans. The proposed chapters are part of the classical paradigm linking the morphology of structures (the spine) to their performance, which produces and controls the various behaviors involving the axial system of the tetrapods, from the head to the coccyx. The proposed volume is intended to be original and innovative in its attempt to integrate knowledge (probably not all) on the role and function of the trunk in tetrapods. The authors, a little "provocative" in their approach, are not keen to separate the functioning of an anatomical system common to all vertebrates according to the treated groups that can be divided into "wild tetrapods, domestic animals and humans." Their intention is to try to offer an illustrated and comprehensible tool for the functioning of this system in the tetrapods during their evolution and to associate, in a multidisciplinary approach, the forms and their functions of the elements of this system which Allows to exploit different habitats while being subjected to phylogenetic, epigenetic and developmental constraints.