Quality of Life: The Assessment, Analysis and Reporting of Patient-reported Outcomes, 3rd Edition

The assessment of patient-reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of clinical trials and other clinical studies.

The analysis and interpretation of quality of life relies on a variety of psychometric and statistical methods which are explained in this book in a non-technical way. The result is a practical guide that covers a wide range of methods and emphasizes the use of simple techniques using numerous examples, with extensive chapters covering detailed qualitative methods, the impact of guidelines, the analysis of ordinal data and bootstrap methods. The material in this third edition reflects current teaching methods and content widened to address continuing developments in item response theory, computer adaptive testing, and analyses with missing data, Bayesian methods, systematic reviews and meta-analysis.

This book is aimed at everyone involved in quality of life research and is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and clinical practice.