Differentiation of Chiral Compounds Using NMR Spectroscopy

Differentiation of Chiral Compounds Using NMR Spectroscopy Second Edition totally updates the 2007 volume in the same concise way as the original volume. While the book does not mention all of the available chiral systems that have been reported in the literature for use in NMR spectroscopy, it focuses most on the systems that are commercially available.  It covers the broad array of reagents that make it possible to determine the optical purity and assign the absolute configuration of many classes of compounds. In addition , it describes chiral NMR discriminating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals, and describes the range and types of compounds for which they can be used for analysis.

The new edition includes recent findings including achiral reagents which when added to mixtures of certain chiral reagents and analyte compounds cause large enhancements in enantiodifferentiation through the formation of ternary complexes as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation.