Biomedical Accelerator Mass Spectrometry

This book covers fundamentals, developments, and applications of biomedical accelerator mass spectrometry (AMS) for the pharmaceutical industry. Providing a comprehensive description of the technology and its primary uses, this book reviews the necessary methods for handling AMS and analyzing data. It begins with the basics of isotopes, radioactivity, and radiotracers in biochemistry and pharmacology. The next few chapters focus on instrumentation, data handling, and sample preparation general principles. The second half of the book covers principles, techniques, and case studies pertaining to DNA binding and cancer, drug metabolism, pharmacokinetics, microdosing, disease studies, proteins, biomedicine, and medical imaging that use AMS. Finally, future perspectives and insights are provided by global leaders and industry experts to pave the way for new discoveries in the field. As a practical guide, this book is essential for researchers and scientists using AMS and professionals in pharmaceutical development.