This book will describe and discuss the development of novel Computer Aided Diagnosis (CAD) software. CAD is a fast growing, global market in which innovative and well-designed products are very sought after and need support in terms of comprehensive understanding of the field, which this book will provide. This book will also describe several examples, in detail, showing the tool in use. It will provide a detailed description of the methodologies and the implementation of algorithms designed to perform the computer aided analysis of 3D medical imagery. It deals specifically with the processes of computer aided detection and characterization of abnormalities associated with disease.