Autophagy, Infection, and the Immune Response

Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection.

Introductory chapters ground the reader by laying out the autophagic pathway from a cellular perspective, and listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma.

Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, the book combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.