The interactions of nanomaterials and nanosystems within bio systems are a concern for all the scientific community. Several groups are working on addressing the issues related to nanosafety and nanotoxicity, but these assessments cannot accurately be made without addressing and defining the unique parameters of nanomaterials. The proposed book will be a collection of chapters addressing the physical assessment of nanomaterials and the link between the nanomaterials properties and observed biological effects. The book will have chapters from distinguished scientists working in this field from many different countries.