A comprehensive review of the role and function of microRNAs in human health, and their potential as novel therapeutics
Since their first formal recognition just over ten years ago, microRNAs (or miRNAs) have become one of the hottest subjects in science and medicine. MiRNAs are key players in practically every biological process examined to date—especially in the area of biomedicine, where miRNAs are recognized as essential physiological regulators and play crucial roles in a wide range of diseases including infectious diseases, hereditary disorders, immunological and heart disease, neurological and psychological disorders, and cancer.
Written by an international team of renowned experts in the field, MicroRNAs in Medicine provides an easy access point into the current literature on miRNAs for both scientists and clinicians, with particular focus on their relevance to medicine. Beginning with an introduction to basic miRNA role and function, this text goes on to cover the importance of miRNAs in normal physiology, infectious and non-infectious diseases, cancer, circulating miRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics.
Starting with a Foreword by Sir David Baulcombe, one of the pioneers of miRNA discovery, MicroRNAs in Medicine provides in-depth and easily accessible coverage of the function of miRNAs in major aspects of medical science, including:
- Stem cell fate and reprogramming
- Adaptive and innate immunity
- Aging and senescence
- Hematopoiesis
- Viruses including HIV
- Malaria
- Cancer
- Hereditary disorders
- Cardiovascular diseases
- Diabetes
- Liver disease
- Neurological and psychological disorders
- Circulating miRNAs as cellular messengers and novel biomarkers
- Therapeutic use of miRNAs
Accessible to both the experienced researcher and those newer to the field, this one-stop source of information is ideal for students, researchers, and clinicians.
