Cellular Domains

The first comprehensive, systematic review of cellular domains

Cellular domains play vital roles in a wide range of cellular functions. Defining cellular domains and understanding the molecular basis of their formation is essential to the study of cell functionality. This authoritative reference provides the most comprehensive analysis available on cellular domains, with emphasis on the definition and molecular composition of the domain as well as the functional implications of domain organization.

Each chapter focuses on a different domain and is supported by figures defining the domain. Highlighting the latest advances in the field, the book's extensive coverage includes:

• Membrane domains—Cytoskeleton-induced meso-scale domains, Clathrin-coated pits, Caveolae, Lipid rafts, and Modeling membrane domains

• Organellar domains—Mitochondria, Endoplasmic reticulum, Golgi apparatus, Endosomes, Lysosomes and phagosomes, and Endoplasmic reticulum junctions

• Cytoskeletal domains—Actin cytoskeleton, Microvilli, Microtubules, Cilia, and Intermediate filaments

• Adhesive and communicating domains—Focal adhesions, Adherens junctions, Tight junctions and desmosomes, and Gap junctions

• Polarized cellular domains—Epithelial domains and Neuronal domains

• Domains regulating gene expression—Nuclear domains, Nuclear pore, and Cytoplasmic RNA domains

Such thorough coverage of the many and various cellular domains makes this a one-stop reference for research scientists as well as advanced students in cell biology, biochemistry, cellular biophysics, and cellular physiology.